Single dad and struggling animal handler Eddie works with lots of creatures, but at home, he has a strict No Pets Allowed policy. He won't let his son Billy keep the adorable stray dog Beethoven and his family of puppies. Beethoven crashes into Hollywood and into Eddie's heart as well.

Adopted by the Newton household's three children, an adorable little St. Bernard puppy grows into 185 pounds of disaster-prone trouble; There's trouble in the heir when Beethoven becomes the proud father of four pups, each one an adorable but mischievous bundle of joy; When two bumbling thieves threaten the safety of his family on vacation, Beethoven sets out to put a bit on the bad guys; It's a case of double trouble when Beethoven is mistaken for...